Spray and pray – the COVID-19 version

Kiran Mazumdar-Shaw is the head of Biocon, a company headquartered in Bengaluru and which has repurposed a drug called itolizumab – already approved to help manage severe chronic psoriasis in different markets – to manage cytokine release syndrome (CRS) in COVID-19 patients. Setting aside CRS's relevance in the COVID-19 pathology (considering it is currently in … Continue reading Spray and pray – the COVID-19 version

New footage of ‘Tsar Bomba’, history’s most powerful nuke

This post was originally published on October 31, 2018. I'm republishing it today after Rosatom, the Russian nuclear energy corporation, released 40 minutes of previously classified footage of RDS-220's explosion on August 28, 2020 (embedded below). This is a minute-long excerpt by Reuters showing the explosion. Fifty-seven years ago on October 30, the Soviets detonated … Continue reading New footage of ‘Tsar Bomba’, history’s most powerful nuke

The matter of a journal’s reputation

Apparently (and surprisingly) The Telegraph didn’t allow Dinesh Thakur to respond to an article by Biocon employee Sundar Ramanan, in which Ramanan deems Thakur’s article about the claims to efficacy of the Biocon drug Itolizumab not being backed by enough data to have received the DCGI’s approval to be inaccurate. Even notwithstanding The Telegraph‘s policy on how rebuttals are … Continue reading The matter of a journal’s reputation

A non-self-correcting science

While I'm all for a bit of triumphalism when some component of conventional publication vis-à-vis scientific research – like pre-publication anonymous peer review – fails, and fails publicly, I spotted an article in The Conversation earlier today that I thought crossed a line (and not in the way you think). In this article, headlined 'Retractions … Continue reading A non-self-correcting science